PepEVOLVE: Position-Aware Dynamic Peptide Optimization via Group-Relative Advantage
arXiv:2511.16912v1 Announce Type: new Abstract: Macrocyclic peptides are an emerging modality that combines biologics-like affinity with small-molecule-like developability, but their vast combinatorial space and multi-parameter objectives make lead optimization slow and challenging. Prior generative approaches such as PepINVENT require chemists…
