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Steering Generative Models with Experimental Data for Protein Fitness Optimization

arXiv:2505.15093v2 Announce Type: replace-cross Abstract: Protein fitness optimization involves finding a protein sequence that maximizes desired quantitative properties in a combinatorially large design space of possible sequences. Recent advances in steering protein generative models (e.g., diffusion models and language models)…

A novel Information-Driven Strategy for Optimal Regression Assessment

arXiv:2510.14222v2 Announce Type: replace-cross Abstract: In Machine Learning (ML), a regression algorithm aims to minimize a loss function based on data. An assessment method in this context seeks to quantify the discrepancy between the optimal response for an input-output system…

Automated Algorithm Design for Auto-Tuning Optimizers

arXiv:2510.17899v1 Announce Type: new Abstract: Automatic performance tuning (auto-tuning) is essential for optimizing high-performance applications, where vast and irregular parameter spaces make manual exploration infeasible. Traditionally, auto-tuning relies on well-established optimization algorithms such as evolutionary algorithms, annealing methods, or surrogate…

Hierarchical Federated Unlearning for Large Language Models

arXiv:2510.17895v1 Announce Type: new Abstract: Large Language Models (LLMs) are increasingly integrated into real-world applications, raising concerns about privacy, security and the need to remove undesirable knowledge. Machine Unlearning has emerged as a promising solution, yet faces two key challenges:…

MIN-Merging: Merge the Important Neurons for Model Merging

arXiv:2510.17890v1 Announce Type: new Abstract: Recent advances in deep learning have led to a surge of open-source models across diverse domains. While model merging offers a promising way to combine their strengths, existing approaches often suffer from parameter conflicts that…