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Benchmark on Drug Target Interaction Modeling from a Drug Structure Perspective

arXiv:2407.04055v2 Announce Type: replace-cross Abstract: The prediction modeling of drug-target interactions is crucial to drug discovery and design, which has seen rapid advancements owing to deep learning technologies. Recently developed methods, such as those based on graph neural networks (GNNs)…

PRIMUS: Pretraining IMU Encoders with Multimodal Self-Supervision

arXiv:2411.15127v3 Announce Type: replace Abstract: Sensing human motions through Inertial Measurement Units (IMUs) embedded in personal devices has enabled significant applications in health and wellness. Labeled IMU data is scarce, however, unlabeled or weakly labeled IMU data can be used…

An Analytical Characterization of Sloppiness in Neural Networks: Insights from Linear Models

arXiv:2505.08915v2 Announce Type: replace Abstract: Recent experiments have shown that training trajectories of multiple deep neural networks with different architectures, optimization algorithms, hyper-parameter settings, and regularization methods evolve on a remarkably low-dimensional “hyper-ribbon-like” manifold in the space of probability distributions.…