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PrismFlow: Residual Dynamics for Flow Matching in Time-Series Generation

arXiv:2605.28867v1 Announce Type: new Abstract: Generating high-quality time-series data is challenging because real-world signals often exhibit multimodal patterns and multiscale dynamics, including oscillations and high-frequency variations. Flow Matching (FM) offers an efficient alternative to diffusion models, but practical implementations typically…

Self-Play Reinforcement Learning under Imperfect Information in Big 2

arXiv:2605.28863v1 Announce Type: new Abstract: Imperfect-information multiplayer games test whether agents can act under hidden information, sparse rewards, and non-stationary opponents. We study these challenges in Big 2, a four-player imperfect-information card game. We develop a self-play RL framework for…

Molecular Lead Optimization via Agentic Tool Planning

arXiv:2605.28862v1 Announce Type: new Abstract: Drug discovery is a lengthy and resource-intensive process composed of multiple stages. Among these stages, lead optimization plays a critical role in transforming early hit compounds into viable drug candidates. This stage requires improving ADMET-related…