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PRISM-CTG: A Foundation Model for Cardiotocography Analysis with Multi-View SSL

arXiv:2605.02917v1 Announce Type: new Abstract: Supervised deep learning models for automated CTG analysis are typically constrained by narrowly curated labelled datasets and limited patient cohorts, leaving substantial volumes of physiologically informative clinical recordings untapped. To address this limitation, we propose…

Expanding functional protein sequence space using high entropy generative models

arXiv:2605.03578v1 Announce Type: cross Abstract: Boltzmann Machines trained on evolutionary sequence data have emerged as a powerful paradigm for the data-driven design of artificial proteins. However, the relationship between model architecture, specifically parameter density, and experimental performance remains poorly understood.…

DeRelayL: Sustainable Decentralized Relay Learning

arXiv:2605.02935v1 Announce Type: new Abstract: In the era of big data, large-scale machine learning models have revolutionized various fields, driving significant advancements. However, large-scale model training demands high financial and computational resources, which are only affordable by a few technological…

Proteo-R1: Reasoning Foundation Models for De Novo Protein Design

arXiv:2605.02937v1 Announce Type: new Abstract: Deep learning in emph{de novo} protein design has achieved atomic-level fidelity. However, existing models remain largely non-deliberative: they directly synthesize molecular geometries without explicitly reasoning about which residues or interactions are functionally essential. As a…